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,The role of metal ions in dopaminergic neuron degeneration in Parkinsonism and Parkinson’s disease,ung copper miners. Interestingly, copper is able to complex with dopamine, which can be taken up by cells expressing the dopamine transporter, inducing caspase-independent cell death with formation of autophagic vacuoles. Iron is also able to form a complex with dopamine, the neurotoxic action of wh