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Molecular and Functional Characteristics of Cloned Human Organic Cation Transporters,t will be years and perhaps several more decades before all of these transporters are cloned and characterized. We have made a good start and there will be years of exciting work and discovery in the organic cation transport field in the future.gratify 发表于 2025-3-22 09:19:59
Organic Anion Transporters,ers probably have physiologically crucial roles, manipulation of drug disposition by utilization of these transporters is expected to be useful for regulating the pharmacokinetics of anionic drugs not only in intestinal absorption and renal and hepatic elimination, but also in distribution into pharmacological target tissues.协奏曲 发表于 2025-3-22 14:56:34
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Drug Transport and Targeting,tinal transporters are located in the brush border membrane as well as basolateral membrane. Each transporter exhibits its own substrate specificity, and some have broader specificities than others. In addition, the distribution and characteristics of the intestinal transporters exhibit regional dif信任 发表于 2025-3-23 03:35:47
Cationic Amino Acid Transporters (CATs),oday, we know that there are at least three different CAT isoforms that mediate y. activity and the family might be growing. In addition, transport systems for cationic amino acids other than y + have been described and proteins that induce the respective transport activities have been identified. C作茧自缚 发表于 2025-3-23 07:20:49
Electrophysiological Analysis of Renal Na+-Coupled Divalent Anion Transporters,tics provides essential information for both model generation and identification of partial reactions in the transport cycle which play a critical role in determining kinetic parameters. Furthermore, the voltage dependence of the apparent affinity constants obtained from the steady state serves to e