卑贱 发表于 2025-3-21 16:04:56
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Electrogenic Na+/HCO 3 − cotransporter NBC1 (SLC4A4): proximal renal tubular acidosis and ocular patBlood and cellular pH are tightly controlled. Normal blood pH is 7.35–7.45, that is,[H. of 36–45nM. In fact, humans with blood pH below 7.2 or above 7.6 are quite sick. Chronic blood pH below 7.0 ([H.=100nM) or above 7.8 (H. ∼ 15nM) is incompatible with life.Ischemic-Stroke 发表于 2025-3-22 09:10:56
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Introductione taken up from the food in only small quantities but are essential components of enzymes, hormones, energy substrates, and nucleic acids, or for the formation of extracellular matrix in bone (phosphate) or cartilage (sulfate). The absolute requirement for these substrates and their often low concen平项山 发表于 2025-3-23 02:03:46
Anion exchangers DTDST (SLC26A2), DRA (SLC26A3), and pendrin (SLC26A4)ns in the body arising from defect s in cell surface (plasma membrane) anion transport. This famil y of proteins, designated /ldsulfate transporters” based on their function, belongs to the Human Genome Nomenclature Committee (HGNC) designated Solute Linked Carrier (SLC) family 26, of which presentl脊椎动物 发表于 2025-3-23 07:17:01
Divalent metal transporter DMT1 (SLC11A2); we will describe the existing mutants representing specific transporter diseases in rodents. In addition, the chapter will further describe the potential contribution of DMT1 to diseases where . is not the gene mutated. Lastly, we will present insights derived from or to be gained from in vitro mu