无缘无故 发表于 2025-3-21 19:29:33
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Activating and Inhibitory NK Cell Receptorsposed a unique mechanism of immune surveillance for ‘missing self’ (1). The molecular mechanism responsible for this phenomenon has been defined by the identification of membrane receptors on NK cells that bind to MHC class I on potential target cells. While the NK cell receptors initiating a cell-mConcrete 发表于 2025-3-22 03:07:42
Regulation of Immune Responses by Inhibitory Receptors them off. In addition, fine-tuning can be achieved through signals that amplify or downmodulate responses. The complexity in signal transduction pathways that regulate these responses is daunting. Even terminal responses, such as degranulation by effector cells in the immune system, do not follow ahankering 发表于 2025-3-22 07:39:58
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Anti-Leishmania Effector Functions of CD4, Th1 Cells and Early Events Instructing Th2 Cell Developmemmalian host. In contrast, mice from BALB strains are unable to control infection and develop progressive disease. Resistance and susceptibility have been correlated with the appearance of parasite-specific Th1 or Th2 cells, respectively(1). Furthermore, the passive transfer of .-specific Th1 or Th2Feedback 发表于 2025-3-22 22:57:31
Genetic Control of the T Cell Response to , Infectionby CD4. Th1 cells (1,2). Th1 cells secrete the potent macrophage activator IFN-γ, thus stimulating effective killing of this parasite (1,3). A few inbred mouse strains, such as BALB/c and SWR, fail to control parasite replication. This failure results in progressive lesion development, spread to vismitral-valve 发表于 2025-3-23 03:56:25
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