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Immunological Tolerance by Antigen-Induced Apoptosis of Mature T Lymphocytesof death by antigen is a feedback regulatory process that controls the intensity of immune responses involving T lymphocytes. We have called this mechanism “propriocidal regulation” and propose that it represents one means by which antigen-induces tolerance. We have recently shown that autoreactiveanimated 发表于 2025-3-23 06:37:03
Control of Lymphopoiesis by Non-Receptor Protein Tyrosine Kinases, which for conventional T cells takes place in the thymus, can be modelled in vitro or in fetal thymic organ culture (3). Detailed analysis of T and B cell development has established that precursor cells proceed through a series of clearly defined maturation steps, giving rise to intermediate cell