Injunction 发表于 2025-3-25 05:49:42
Switching Genes on and off: The Example of Nuclear Receptorsle of nuclear receptors..In this Chapter, we will discuss principles of nuclear receptor signaling and the subdivision of the nuclear receptor superfamily into three sub-classes. Then we will have a look on the different molecular interactions of nuclear receptors. Furthermore, the physiological act上腭 发表于 2025-3-25 08:07:40
Mapping the Genomeeracting nuclear proteins and may not always directly contact DNA. This new insight has also consequences on the question, which transcription factor is assigned to the regulation of which gene, i.e. not always the approach applies that sites in rather close vicinity to TSS regions are the main regi舔食 发表于 2025-3-25 11:53:48
http://reply.papertrans.cn/63/6288/628720/628720_23.png彻底检查 发表于 2025-3-25 15:51:02
http://reply.papertrans.cn/63/6288/628720/628720_24.png讲个故事逗他 发表于 2025-3-25 20:04:37
http://reply.papertrans.cn/63/6288/628720/628720_25.pngBridle 发表于 2025-3-26 02:05:24
Chromatin Remodelingtate to an active state. Pioneer transcription factors are the first that bind a closed promoter and play an important role in providing access to other sequence-specific transcription factors. Furthermore, regulatory genomic regions are now understood as dynamic structures, showing high turnover offulmination 发表于 2025-3-26 05:26:55
http://reply.papertrans.cn/63/6288/628720/628720_27.pngAprope 发表于 2025-3-26 11:35:20
Regulatory RNA or more proteins into a spatial proximity or iii) as guides to recruit proteins, such as chromatin modifying enzymes, to genomic DNA. A special variant of long ncRNAs are enhancer RNAs (eRNAs), which are produced bidirectionally at enhancer regions, when the latter interact with promoter regions..mCHARM 发表于 2025-3-26 13:41:46
http://reply.papertrans.cn/63/6288/628720/628720_29.png刺耳 发表于 2025-3-26 17:46:00
tion of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is t978-94-007-7905-1