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Erich Hecker,Friedrich Rippmann graduates, teachers, and researchers in optimization, operations research, computational mathematics, applied mathematics, and some engineering and economics. It will also be useful for scientists in engineering and economics. .978-1-4419-3765-0978-0-387-24976-6Series ISSN 1931-6828 Series E-ISSN 1931-6836
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Mechanisms of Environmental Mutagenesis-Carcinogenesis
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Mechanisms of Environmental Mutagenesis-Carcinogenesis978-1-4615-3808-0
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Mutation Spectrum in Carcinogenicityin DNA in cancer induction is beyond any reasonable doubts, the actual relationship between mutagenic and carcinogenic properties of chemicals is more complex than previously conceived. A primary reason for this complexity is the multistep nature of cancer induction, which implies both genetic and n
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Ultraviolet Light Mutagenesis in Bacteria: The Possible Role of a DNA Polymerase III Complex Lackingppearance of a newly induced mutation reflected a failure of the normal error-correcting mechanisms (Bridges, 1980). The three error-correcting mechanisms discussed then were DNA polymerase base selection, exonucleolytic proofreading, and mismatch correction. Ten years later the same topics appear,
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Centromere Separation: Emerging Relationship with Aneuploidyuence (Vig and Rattner, 1989). In humans, for example, the centromeres of chromosomes 18, 17 and 2 separate before do others and all acrocentrics carrying large quantity of r-DNA separate the last. Similarly, amongst the three pairs of chromosomes of the plant . the largest chromosome is the first t
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Genetic Analysis of Genotoxic Effects on Chromosomes and Cell Division in Lower Eukaryotes in molecular terms, are the vulnerable targets sufficiently conserved that similar effects can be expected in higher organisms? (ii) How informative and conclusive are the tests developed in lower eukaryotes? i.e., can genetic tests identify induced primary aneuploidy and distiguish such events fro
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