柳条筐
发表于 2025-3-21 19:38:43
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残酷的地方
发表于 2025-3-22 00:01:17
eoxyribozymes have become increasingly valuable molecular tools in the form of switches and sensors. Unfortunately, binding or catalytic actions by these switches and sensors do not usually lead to an easily detectable signal, and the lack of a facile reporting method could substantially reduce thei
不妥协
发表于 2025-3-22 02:41:32
Matthias Plaue,Mike Scherfnertional group to the RNA-aminoglycoside complex formation. In addition, various biochemical and microbiological data as well as some resistance and toxicity mechanisms could be rationalized at the molecular level. It was demonstrated that the binding of the aminoglycosides locks the A site into a con
Afflict
发表于 2025-3-22 07:45:50
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有机体
发表于 2025-3-22 10:03:28
Matthias Plaue,Mike Scherfnerin complex with the pre-mRNA to catalyze pre-messenger-RNA splicing has also been proposed .. It is highly likely that additional RNA catalytic motifs and new roles for RNA-mediated catalysis will also be found as we learn more about the genomes of a variety of organisms.
chandel
发表于 2025-3-22 15:24:00
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新星
发表于 2025-3-22 20:43:53
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诱惑
发表于 2025-3-23 00:19:17
Matthias Plaue,Mike Scherfner have the advantage of being independent of RNase H; however, they lack the natural chemical and biological stability possessed by the antisense DNA oligonucleotide (ON). Although it is possible to manufacture biologically active RNA, its relative fragility in this environment makes it difficult to
鬼魂
发表于 2025-3-23 04:37:56
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采纳
发表于 2025-3-23 09:11:38
Matthias Plaue,Mike Scherfneral years that the formation of double-stranded RNA (dsRNA), triggers a variety of cellular effects that depend not only on the length of the RNA duplex, but also on its intracellular location and on the cell type .. These effects include activation of the protein kinase (PKR) and RNase L pathways, i