附录
发表于 2025-3-25 03:48:07
Matthias Schubertion of basic metabolic programs as well as by activation of CD4 T cell lineage-specific genes. Outlining both unifying principles involved in Notch-mediated T cell fate decisions and context-specific differences may lead the way to successful therapeutic exploitation of this pathway in immunity.
含沙射影
发表于 2025-3-25 10:32:16
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玩笑
发表于 2025-3-25 15:12:01
Matthias Schubert. in recent years. Using gene synthesis and site-directed mutagenesis, we generated a series of . genomic transgenes which harbor mutations in all or specific subsets of Notch .-glucose sites. Gene dosage and rescue experiments in animals raised at various temperatures allowed us to dissect the cont
patriarch
发表于 2025-3-25 16:11:11
Matthias Schubertnal characterization of variants in these “genes of unknown significance” continues to increase. In this chapter, we describe a workflow to functionally characterize a rare variant in a Notch signaling related gene that was found to be associated with late-onset Alzheimer’s disease. This pipeline in
流眼泪
发表于 2025-3-25 23:52:49
Matthias Schubertression of many types of cancer. Moreover, these new scientific findings have shown promise in opening new avenues for cancer prevention and therapy, although this goal is still challenging. Vol. III of the second edition of the book . entitled ., summarizes important recent developments in this fas
PURG
发表于 2025-3-26 03:14:05
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牙齿
发表于 2025-3-26 06:00:49
Matthias Schubert or loss or NOTCH1 activity promotes the development of human papillomavirus (HPV)–associated cancers. The additional HPV oncogenes likely disrupt the tumor-suppressive activities of NOTCH and enable the oncogenic pathways activated by NOTCH to promote tumor growth. In this review, we detail the rol
软膏
发表于 2025-3-26 10:28:25
Matthias Schubertl death as well as JNK activation. Considering the fact of well conserved nature of Notch as well as both of these two proteins, namely, Hrp48 and Deltex, this interaction can be helpful to understand the regulation of Notch signaling both in development and disease condition.
过于平凡
发表于 2025-3-26 16:14:44
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infelicitous
发表于 2025-3-26 17:44:24
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