False-Negative 发表于 2025-3-21 18:59:15

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滴注 发表于 2025-3-21 23:07:07

Diffusion Processes, a deterministic framework, these models also raise the mathematical bar. The current chapter surveys the theory at an elementary level, stressing intuition rather than rigor. Readers with the time and mathematical background should follow up this brief account by delving into serious presentations of the mathematics .

刀锋 发表于 2025-3-22 02:38:51

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爱得痛了 发表于 2025-3-22 07:34:39

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Inkling 发表于 2025-3-22 09:15:52

Computation of Mendelian Likelihoods,of the story. Evaluation of pedigree likelihoods remains a subject sorely in need of further theoretical improvement. Linkage calculations alone are among the most demanding computational tasks in modern biology.

Mercurial 发表于 2025-3-22 13:46:00

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penance 发表于 2025-3-22 18:49:16

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Confidential 发表于 2025-3-23 00:58:18

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CUB 发表于 2025-3-23 03:34:42

Counting Methods and the EM Algorithm,ted by Dempster et al. . Our initial example retraces some of the steps in the long march from concrete problems to an abstract algorithm applicable to an astonishing variety of statistical models.

反省 发表于 2025-3-23 07:21:29

,Newton’s Method and Scoring, have much to offer in small to moderate-sized problems. For those uncomfortable with pulling prior distributions out of thin air, . procedures can be an appealing compromise between classical and Bayesian methods. This chapter illustrates some of these well-known themes in the context of allele frequency estimation and linkage analysis.
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查看完整版本: Titlebook: Mathematical and Statistical Methods for Genetic Analysis; Kenneth Lange Textbook 2002Latest edition Springer Science+Business Media New Y