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Emanuela Rosazza Gianin,Carlo Sgarrals. In these niches, growth factors and extracellular matrix (ECM) molecules determine the fate of neural stem and progenitor cells (NSPC). However, the precise compounds and the mechanisms that regulate growth factors and other signaling molecules in the niches are unknown. Based on the evidence th切割 发表于 2025-3-29 00:37:07
Emanuela Rosazza Gianin,Carlo Sgarraolecular biology of adult neurogenesis.Chapters on the clini.The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed t丰满中国 发表于 2025-3-29 04:18:57
Emanuela Rosazza Gianin,Carlo Sgarra brain areas and relative rates of cell proliferation 10–100 times higher than in the adult mammalian brain. The source of the new cells are stem cells in distinct proliferation zones, which give rise to both neurons and glial cells. Depending on the brain region, the young cells either reside in c恶臭 发表于 2025-3-29 08:28:19
Emanuela Rosazza Gianin,Carlo Sgarra walls of the lateral ventricles, mainly in the sulci. The putative neural progenitors are radial glial cells. These glial cells give rise to neuroblasts that migrate to their final destination. In general, the new neurons are born in the portion of the ventricular zone (VZ) adjacent to the telencepglisten 发表于 2025-3-29 12:36:51
Emanuela Rosazza Gianin,Carlo Sgarraregenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides the foundations of the field. Today, adult neurogenesis is a rapidly expanding discipline applicable to the study of brain development and diseases,欢乐中国 发表于 2025-3-29 18:43:51
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he first part, we will review the specific features and advantages of the . model and highlight why it is particularly suited for systems biology approaches to bridge our understanding at the molecular/genetic, cellular, circuit, and behavioral levels. In the second part, we will present how . can b