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Edward S. Deevey Jr.the subject, from broad description and basic points up to fDavid R. Brown Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK In 1982 Stanley Prusiner and colleagues puri?ed an abnormal protein from the brains of mice experimentally infected with a rare sheep dis- 1 ease caEeg332 发表于 2025-3-29 02:49:48
monitoring the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy of cMRI to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMROvulation 发表于 2025-3-29 04:20:37
Johann Peter Süssmilchse techniques evidence that MS is not only a white matter di.In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic confidence and for monitoring the efficacy of experimental treatment. However, cMRI has limited specificityFATAL 发表于 2025-3-29 10:07:20
Leonard Eulerultiple sclerosis (MS), since they provide a quite reliable, even though indirect, measure of the extent of demyelination or axonal loss in a given nerve pathway. For this reason, they are used to indicate the involvement of sensory and motor pathways in the presence of vague disturbances and to detnitric-oxide 发表于 2025-3-29 14:27:45
Alfred J. Lotka sclerosis (MS) [.] with the ultimate goal of increasing our understanding of the mechanisms responsible for the accumulation of irreversible disability. The application of these techniques has provided important insights into the pathobiology of MS. First, it has been demonstrated that MS-related d拖网 发表于 2025-3-29 16:56:46
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e could not be infected because they lacked expression of the protein that was now 3,4 forever linked to these disease . Since then it has become more widely accepted for these diseases to be termed prion disea978-1-4899-8688-7978-0-387-23923-1