cacophony 发表于 2025-3-26 21:39:09
tential. These changes of fibroblasts membrane potential are determined by operation of mechano-gated channel (MGCs). Two types of MGCs with conductances of 43 pS and 87 pS were observed during direct deformation of the fresh isolated cells. Cell compression augment the whole-cell MG currents and inRENAL 发表于 2025-3-27 02:47:50
Daniel Bartholomewole in physiological heart development and hypertrophy, but disruption of the well-balanced stress-sensing machinery causes mechanical dysregulation, cardiac remodelling, and heart failure. In cardiomyocytes, nodal points of force transmission and mechanosensing reside in the Z-disk, M-band, and I-b拔出 发表于 2025-3-27 05:50:40
http://reply.papertrans.cn/63/6239/623895/623895_33.png陶器 发表于 2025-3-27 11:46:51
Daniel Bartholomewseen during neonatal development or in the hypertensive adult promote a fibrotic response in the heart. In vitro studies have established that mechanical stretch of isolated cardiac fibroblasts directly stimulates expression of extracellular matrix components and proliferation, both hallmarks of fib仪式 发表于 2025-3-27 15:38:03
transductive capacity of the intestine. Mechanosensitivity is conferred by both extrinsic and intrinsic pathways in the gut and includes non-neuronal elements. This review focuses on the neuronal mechanosensitive elements within the GI tract and describes their functional and neuroanatomical feature思想流动 发表于 2025-3-27 20:46:08
Daniel Bartholomewtransductive capacity of the intestine. Mechanosensitivity is conferred by both extrinsic and intrinsic pathways in the gut and includes non-neuronal elements. This review focuses on the neuronal mechanosensitive elements within the GI tract and describes their functional and neuroanatomical featurepersistence 发表于 2025-3-28 01:46:33
Daniel Bartholomewynamic loading. Because stress-strain responses are inherently intrinsic, the review is focused on physical and computational models using the finite element method. In order to maintain the focus, although experimental animal models are used as validations tools for ensuring the confidence in the facrimony 发表于 2025-3-28 02:45:47
Daniel Bartholomewnism in the cochlea. It is suggested that passive calcium-independent slow motility induced by hyposmotic activation may have physiological or pathological significance even in normal or impaired hearing of cochlear origin. The cell swelling induced by hyposmotic stimulation has been shown to be accDEFT 发表于 2025-3-28 09:32:44
Daniel Bartholomewnism in the cochlea. It is suggested that passive calcium-independent slow motility induced by hyposmotic activation may have physiological or pathological significance even in normal or impaired hearing of cochlear origin. The cell swelling induced by hyposmotic stimulation has been shown to be acccontrast-medium 发表于 2025-3-28 11:57:48
ng the recent developments on the study of mechanotransducti.This book offers an essential introduction for all graduate students and researchers who are working on or interested in mechanotransduction using fruit flies as their model organisms. Designed for accessibility, it follows a simple five-c