HERE 发表于 2025-3-26 21:13:43
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The Voice of Truth: A Reading of e stories — . and . — were already written, yet it was almost three years before the second series was actually published. . made up the trilogy: its place there was a hurried addition after the manuscript had been subjected to some interesting major changes.高谈阔论 发表于 2025-3-27 12:33:01
by different activities. While initially it appears that such adaptation could be explained by load-induced bone formation and disuse-induced bone resorption, such ideas rapidly become too simplistic to explain many observations of skeletal physiology. When examined in more detail, these require thFigate 发表于 2025-3-27 13:54:24
Brian Hollingworthed by a large complex of cytoplasmic proteins linking adhesive molecules to cytoskeletons. To explore the molecular mechanisms underlying the force-dependent cell responses including remodeling of cytoskeletons, focal adhesive contacts, and of cell-shapes, it is crucial to apply precisely controlled豪华 发表于 2025-3-27 20:56:54
ronauts and bedridden patients suffer muscle and bone loss from lack of use. Even the heart, in pumping blood, causes mechanical stress to itself and to vascular tissue. With the loss of mechanical stress, homeostasis becomes impaired and leads to pathological conditions such as osteopenia, muscle aCRAB 发表于 2025-3-27 22:40:18
Brian Hollingworth53 gene related to apoptosis and platelet endothelial cell adhesion molecule-1 (PECAM-1) related to osteoblast differentiation...: We used tibial samples of tail-suspended mice. Histomorphometric analyses were done at the secondary spongiosa of the proximal tibia. Bone formation was evaluated with fBOOST 发表于 2025-3-28 02:25:50
Brian Hollingworths, β pleated sheets, random coils, and collagen coiled-coils that form supra-molecular structures that maintain cell and tissue shape, resist mechanical forces, act to transmit loads, generate contractile forces, provide a mechanical link between extracellular matrix and the cell cytoskeleton, and a繁殖 发表于 2025-3-28 08:32:25
Brian Hollingworth still struggling with developing models of more complex ECMs such as vessel wall. In vessel wall the series connection between collagen and smooth muscle is likely the important link between external loading and up-regulation of mechanochemical transduction. However, we still can only dream of form坦白 发表于 2025-3-28 14:28:47
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