PRE 发表于 2025-3-26 21:40:57
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Male Hypogonadism Due to Cancer and Cancer Treatments, resulting in impaired testosterone production. This chapter describes the effects of cancer and its treatment on male reproductive function in terms of damage to the seminiferous epithelium and testosterone production. We also discuss the options, both established and experimental, for fertility preservation in these patients.Melanoma 发表于 2025-3-27 12:04:27
The Human Leydig Cell,e fetal Leydig cell population persists into adulthood in mice but becomes secondary to the adult population. Development of the adult Leydig cell population is dependent on the Sertoli cells and on luteinizing hormone (LH) from the pituitary. The adult cells in humans secrete mainly testosterone sy荧光 发表于 2025-3-27 15:06:06
Normal and Delayed Puberty,on or short courses of low-dose sex steroid supplementation. More complex and involved management is required in males with hypogonadism to achieve both the development of secondary sexual characteristics and to maximize the potential for fertility.antiquated 发表于 2025-3-27 21:05:10
Congenital Hypogonadotropic Hypogonadism in Males: Clinical Features and Pathophysiology,iderable phenotypic heterogeneity in the clinical presentation of CHH, and, in addition to the typical KS and nCHH presentations, several variant forms of CHH are recognized including fertile eunuch variant, adult-onset CHH, and, more recently, reversible forms of CHH, wherein CHH recovers in adulthObverse 发表于 2025-3-28 01:29:25
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Male Hypogonadism and Liver Disease,n the majority of individuals. However, this finding is not uniform, likely related in part to pre-existing metabolic damage, immunosuppression, graft function, and potentially other comorbidities. Further research is needed on the efficacy and safety of testosterone treatment in liver disease.