iodides
发表于 2025-3-25 03:59:29
Introduction: Brief Historical Overview of attack throughout evolution. The most powerful way of damaging a membrane is through the insertion of pore-forming proteins. Research over the last decades shows that such proteins are produced by bacteria to attack bacterial or eukaryotic cells, vertebrates to kill invading organisms or infecte
粗鲁性质
发表于 2025-3-25 10:04:43
Distribution of MACPF/CDC Proteinsspread in nature. MACPFs and CDCs were discovered separately with no sequence similarity at that stage being apparent between the two protein families such that they were not, until recently, considered evolutionary related. The breakthrough showing they are came with recent structural work that als
蛙鸣声
发表于 2025-3-25 15:43:52
http://reply.papertrans.cn/63/6201/620021/620021_23.png
cunning
发表于 2025-3-25 16:33:27
http://reply.papertrans.cn/63/6201/620021/620021_24.png
conifer
发表于 2025-3-25 23:18:03
Perfringolysin O Structure and Mechanism of Pore Formation as a Paradigm for Cholesterol-Dependent C pores by inserting a large β-barrel into cholesterol-containing membrane bilayers. Binding of water-soluble CDCs to the membrane triggers the formation of oligomers containing 35–50 monomers. The coordinated insertion of more than seventy β-hairpins into the membrane requires multiple structural co
MOTTO
发表于 2025-3-26 02:53:11
Structural Biology of the Membrane Attack Complex leads to recruitment of inflammatory cells or opsonisation or killing of pathogens. One effector arm of this network is the terminal pathway of complement, which leads to the formation of the membrane attack complex (MAC) composed of complement components C5b, C6, C7, C8 and C9. Upon formation of C
nutrition
发表于 2025-3-26 07:19:47
http://reply.papertrans.cn/63/6201/620021/620021_27.png
诱导
发表于 2025-3-26 11:10:09
The Biology of Pneumolysin in the diseases caused by . (the pneumococcus). This chapter describes the role of PLY in some of the key process in disease. These include induction of cell death by pore formation and toxin-induced apoptosis as well as more subtle effects on gene expression of host cells including epigenetic effe
COLIC
发表于 2025-3-26 13:39:39
http://reply.papertrans.cn/63/6201/620021/620021_29.png
jocular
发表于 2025-3-26 18:57:47
http://reply.papertrans.cn/63/6201/620021/620021_30.png