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发表于 2025-3-25 03:19:44
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一再遛
发表于 2025-3-25 14:09:04
Hit Triage: Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery,age in drug discovery. It explains, in general, the sources of hits for a drug discovery program and explores the link between potency and efficiency in evaluating lead matter. The chapter then illustrates the collection of both pharmacokinetic data as well as safety data, and describes the relevanc
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发表于 2025-3-25 16:29:51
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相同
发表于 2025-3-25 23:31:50
NMR Spectroscopy in Fragment Based Drug Design,ecular interactions. By way of examples, we will illustrate the unique advantages that these techniques offer when employed in conjunction with fragment-based ligand design, especially when tackling challenging drug targets.
connoisseur
发表于 2025-3-26 00:12:17
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发表于 2025-3-26 06:46:47
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fructose
发表于 2025-3-26 08:57:27
Book 2010 an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of co
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发表于 2025-3-26 14:09:28
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社团
发表于 2025-3-26 20:11:58
Hit Triage: Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery,e of that data and the process of using it to make decisions. Of course, there is no one “right” or “wrong” way to do the work contained in this chapter, but the practice of efficiently building a network of information on compounds, and then using that to make informed decisions can help to shift the odds of success in drug discovery.