胆汁
发表于 2025-3-26 23:44:36
Chih-Po Wen,Soumen Chakrabarti,Etienne Deprit,Arvind Krishnamurthy,Katherine Yelickthe level of synaptic protection. Biochemical isolation of synaptic fractions and immunocytochemistry has localized a set of constitutive and stress-inducible heat shock proteins to components of the synapse. Constitutively expressed Hsc70 protein is enriched in neural tissue compared to non-neural
diathermy
发表于 2025-3-27 01:54:08
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座右铭
发表于 2025-3-27 08:11:54
Balaram Sinharoyiseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV). Key basic and clinical research laboratories from major u
HAWK
发表于 2025-3-27 10:56:20
Seth Copen Goldstein,Klaus Erik Schauser,David Cullertagged polyglutamine constructs were injected into the striatum to generate a chronic model of polyglutamine disease. Furthermore, the lentiviral-mediated expression of Hsj1A was shown to decrease the number of neurons containing inclusions. These and other studies suggest that unlike other HSP40 me
正常
发表于 2025-3-27 14:48:24
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Parley
发表于 2025-3-27 21:16:15
Ken Kennedy,Nenad Nedeljković,Ajay Sethiethal ischaemia has extended the therapeutic potential of the now well known ischaemic preconditioning phenomenon. In this respect, attention has focussed primarily on the inducible isoform of HSP70, rather than the constitutive HSC70, as
Cytokines
发表于 2025-3-28 00:10:28
Ian T. Foster,David R. Kohr Jr.,Robert Olson,Steven Tuecke,Ming Q. Xue Hsp90 machinery regulates protein function. By forming stable client protein•Hsp90 heterocomplexes, the machinery performs its protein quality control function in preventing further cleft unfolding that triggers chaperone-dependent ubiquitination and proteasomal degradation. Natural mutations occu
美学
发表于 2025-3-28 04:00:29
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嘴唇可修剪
发表于 2025-3-28 09:58:21
Gregory D. Benson,Ronald A. Olssonsruption of multiple processes critical to tumor cell growth and survival. Now, great enthusiasm exists over the prospect of targeting Hsp90 function to treat cancer. New chemotypes with improved pharmacology are being developed and clinical trials have demonstrated that Hsp90 function can be inhibi
宽度
发表于 2025-3-28 10:33:42
Gagan Agrawal,Guy Edjlali,Alan Sussman,Jim Humphries,Joel Saltz-crystallin limit the formation of oxidized macromolecules by stimulating the anti-oxidant defences of cell. Hsp27 and αB-crystallin also negatively regulate apoptosis through their ability to interact with several key components of the apoptotic signalling pathway. Moreover, particular oligomeric f