Mortal 发表于 2025-3-30 08:48:28
H. Merlive real-time PCR or high-throughput sequencing can be used, giving either measurement of methylation at a single locus or across the entire genome, respectively. While the data produced by single locus assays is relatively simple to analyze and interpret, global assays such as microarrays or high-t我就不公正 发表于 2025-3-30 14:20:13
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H. G. Zapotoczkyprinting in human neoplasia. We describe data linking three imprinted genes on chromosome 11p15.5, ., and ., to the pathogenesis of Wilms’ tumor (WT) and other neoplasms, as well as to the fetal overgrowth associated with the Beckwith-Wiedemann Syndrome(BWS). We discuss evidence for epimutations at蒸发 发表于 2025-3-31 00:34:03
http://reply.papertrans.cn/55/5437/543667/543667_54.pngDefault 发表于 2025-3-31 03:56:18
A.-R. Laireiterve deleterious consequences than a disruption of an unimprinted gene..There is more to a gene than its DNA sequence. C. H. Waddington used the term “epigenetic” to describe biological differences between tissues that result from the process of development.,.. Waddington needed a new term to describeCondyle 发表于 2025-3-31 08:29:10
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G. Klug,B. Fuchs-Niederngelman syndrome AS patients, however, have generally been synchronous (5,6,14). Furthermore, an investigation of the kinetics of allele-specific replication timing in the GABRB3/A5 cluster on 15q11-13 revealed that cells from PWS and AS have lost the strict replication timing observed on the parent痛恨 发表于 2025-3-31 17:08:15
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http://reply.papertrans.cn/55/5437/543667/543667_59.pngGROVE 发表于 2025-4-1 00:16:08
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