Decibel
发表于 2025-3-26 22:04:35
Kinesin-13 Microtubule Depolymerizing Proteins as Targets for Cancer Therapy,rly effective targets for drug development. This chapter reviews the activities of kinesin-13 proteins in the context of how they might be manipulated to affect spindle structure and advance cancer treatment by direct targeting, by enhancing the effectiveness of other current treatments, or by reversing resistance to other treatments.
脾气暴躁的人
发表于 2025-3-27 04:31:16
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逃避系列单词
发表于 2025-3-27 07:38:35
evance of kinesins to cancer treatment.Contributes to potent.This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting t
backdrop
发表于 2025-3-27 11:08:14
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北极人
发表于 2025-3-27 15:11:05
Kif15: A Useful Target for Anti-cancer Therapy?, to the central player in mediating Eg5-independent bipolar spindle assembly. In this chapter, we describe the function of Kif15 during mitosis and discuss if Kif15 could be a target for drug development in anticancer therapy.
heterogeneous
发表于 2025-3-27 20:30:17
Kinesin-8 Members and Their Potential as Biomarker or Therapeutic Target, the increased abundance may reflect a higher percentage of proliferative cells. Reduction of Kinesin-8 delays cells in mitosis and perturbs microtubule dynamics. Inhibitors of Kinesin-8 may therefore influence the proliferative capacity or may impair the migratory potential of cancer cells. These ideas remain to be tested.
indecipherable
发表于 2025-3-27 23:06:25
Clinical Trials of Mitotic Kinesin Inhibitors,nd less toxic inhibitors of the mitotic process. In this chapter, I review the clinical experience with one group of inhibitors that target mitotic kinesins. I will discuss the results of phase I and II trials with these drugs and place the results of these trials in a context to explain how they can be utilized in future human studies.
Pageant
发表于 2025-3-28 02:36:51
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minimal
发表于 2025-3-28 08:16:01
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OCTO
发表于 2025-3-28 11:14:09
978-94-024-0365-7Springer Science+Business Media Dordrecht 2015