泥瓦匠
发表于 2025-3-23 09:54:54
Assessing Efficacy Data,n of clinical concern. Efficacy is assessed in two ways: there must be compelling evidence of both statistically significant efficacy and clinically significant efficacy. The former is addressed via formalized hypothesis testing involving the creation of a research question, a research hypothesis, a
intrigue
发表于 2025-3-23 14:01:25
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亲密
发表于 2025-3-23 20:26:24
Meta-Methodology,me research question. It commonly involves not only the statistical combination of summary statistics from various trials (study-level data), but also refers to analyses performed on the combination of subject-level data. Reasons for employing this methodology include: providing a more precise estim
假
发表于 2025-3-24 00:30:03
,Benefit–Risk Estimation,rapy. It requires consideration of both benefit and risk. For a drug to receive regulatory approval, the regulatory agency must find a drug to have a favorable benefit–risk profile: The benefit to the population as a whole must outweigh any potential risk to certain individuals, who will be protecte
Ointment
发表于 2025-3-24 05:50:32
J. Rick TurnerDiscusses key statistical concepts.Includes supplementary material:
OVERT
发表于 2025-3-24 10:07:30
SpringerBriefs in Pharmaceutical Science & Drug Developmenthttp://image.papertrans.cn/k/image/542590.jpg
愉快吗
发表于 2025-3-24 11:18:55
Key Statistical Concepts in Clinical Trials for Pharma978-1-4614-1662-3Series ISSN 1864-8118 Series E-ISSN 1864-8126
埋葬
发表于 2025-3-24 18:46:22
https://doi.org/10.1007/978-1-4614-1662-3Clinical Trials; Pharma; Statistical Concepts; Statistics
中古
发表于 2025-3-24 22:26:14
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insincerity
发表于 2025-3-25 01:28:43
Book 2012prove a new drug for marketing) and the individual patient level (by physicians and their patients when deciding whether or not the patient should be prescribed a drug that is on the market). These concepts include drug safety and efficacy, statistical significance, clinical significance, and benefit-risk balance.