魔鬼在游行
发表于 2025-3-26 21:57:03
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裁决
发表于 2025-3-27 03:56:04
K. G. Ober, where EpiEditors consisting of a DNA binding part for targeting and an enzymatic part for rewriting of chromatin modifications are applied in cells to alter chromatin modifications at targeted genome loci in a directed manner. Pioneering studies preceding this era indicated causal relationships of
图画文字
发表于 2025-3-27 08:39:19
S. B. Gusberg,John Rudolph epigenome editors to virtually any genomic site. This advancement in DNA-targeting technology brings allele-specific epigenome editing into reach, a “super-specific” variation of epigenome editing whose goal is an alteration of chromatin marks at only one selected allele of the genomic target locus
analogous
发表于 2025-3-27 10:09:50
Langdon Parsonsposing into epigenetic editing platforms, offer enormous potential as safe and customizable therapies for cancer. Specifically, various transcriptional abnormalities in human malignancies, such as silencing of tumor suppressors and ectopic re-expression of oncogenes, have been successfully targeted
钝剑
发表于 2025-3-27 16:39:35
E. Navratilecisely alter complex cellular pathways with a single intervention. Thus far, this has been typically exploited in combination with genome editing tools (i.e., base−/prime-editing, designer nucleases) to enable simultaneous genetic alterations and modulate complex physiologic cellular pathways. In t
nuclear-tests
发表于 2025-3-27 20:40:10
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大笑
发表于 2025-3-28 01:54:02
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crescendo
发表于 2025-3-28 03:14:18
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护航舰
发表于 2025-3-28 08:38:59
Individualization of Treatment for Cancer of the Cervixr elect combinations thereof. In order to make this choice dependent upon patient factors rather than therapist factors, by which I mean the training, temperament, departmental policy or other variables related to the physician in charge, we must utilize the biological parameters clinically available for this decision.
octogenarian
发表于 2025-3-28 12:52:30
Polycystic Ovarian Disease . and . brought some order out of chaos by defining a syndrome of polycystic ovaries in which wedge resection, in properly selected cases, was very successful. Since 1950 their results have been confirmed by many observers throughout the world.