Perennial长期的 发表于 2025-3-23 11:17:47
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Universal and Specific Functions of STAT3 in Solid Tumours,s. Moreover, STAT3 was recently shown to play unexpected roles in regulating cell metabolism and mitochondrial activity via both transcriptional and non-transcriptional mechanisms. Here, we review the main knowledge about the role of STAT3 in solid tumours, with a particular focus on breast cancer and our recent work with mouse models.ANA 发表于 2025-3-24 08:56:50
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The Continuing Fascination with Jaks and Stats: An Introduction,ge Stark were fascinated by the fact that gene transcription could be induced within minutes after treating cells with type I interferons (IFN-I). The speed with which a signal generated by the plasma membrane–associated IFN-I receptor travelled to nuclear target genes suggested few intermediate steExonerate 发表于 2025-3-24 18:06:26
Regulation of JAKs: Insights Gleaned from the Functional Protein Domains, 15 years until a first crystal structure of a Janus kinase domain was described and by today the structures of all four kinase domains have been explored. In this chapter we discuss the effects of the different JAK domains on the activity, trafficking and localisation of JAKs that were reported introponins 发表于 2025-3-24 19:26:04
http://reply.papertrans.cn/51/5004/500358/500358_19.png马赛克 发表于 2025-3-24 23:53:43
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