SOB
发表于 2025-3-28 15:27:56
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Kinetic
发表于 2025-3-28 19:12:10
Relationship Between Serum Concentrations of Nitisinone and Its Effect on Homogentisic Acid and Tyr). Nitisinone decreases HGA in AKU, but the concentration–response relationship has not been previously reported...: To determine the relationship between serum concentrations of nitisinone and the effect on both HGA and tyrosine; secondly to determine steady-state pharmacokinetics of nitisinone in
Aerate
发表于 2025-3-28 22:56:23
Investigating the Robustness and Diagnostic Potential of Extracellular Matrix Remodelling Biomarkerding trial for nitisinone treatment of AKU patients. We tested a panel of serum and urinary biomarkers reflecting extracellular matrix remodelling (ECMR) of cartilage, bone and connective tissue in SONIA 1 patients to identify non-invasive and diagnostic biomarkers of tissue turnover in AKU...: Fast
multiply
发表于 2025-3-29 07:00:15
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VALID
发表于 2025-3-29 07:36:21
Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice, in the catabolism of phenylalanine and tyrosine. Loss of HGD function prevents metabolism of homogentisic acid (HGA), leading to increased levels of plasma HGA and urinary excretion. Excess HGA becomes deposited in collagenous tissues and subsequently undergoes polymerisation, principally in the ca
intertwine
发表于 2025-3-29 14:14:28
The Pigment in Alkaptonuria Relationship to Melanin and Other Coloured Substances: A Review of Metaain pigment melanin in defining its biochemistry, the different types and function. However, analytical techniques to show these differences in vivo are still not readily available. NMR and IR spectroscopy are relatively insensitive and reveal only major structural differences. Techniques utilising
奴才
发表于 2025-3-29 17:09:18
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啜泣
发表于 2025-3-29 22:42:53
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消耗
发表于 2025-3-30 00:05:18
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国家明智
发表于 2025-3-30 07:36:59
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