Titlebook: Islets of Langerhans; Md. Shahidul Islam Living reference work 20200th edition

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,Clinical Approaches to Preserving β-Cell Function in Diabetes,the time of diagnosis and there was a reduction of β-cell mass of about 60 % at necropsy (accelerated apoptosis). Among the interventions to preserve the β-cells, those that lead to short-term improvement of β-cell secretion are weight loss, metformin, sulfonylureas, and insulin. Long-term improveme

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Electrical, Calcium, and Metabolic Oscillations in Pancreatic Islets, bursting. We discuss the underlying mechanisms for bursting oscillations in mouse islets and the parallel oscillations in intracellular calcium and metabolism. We present a unified biophysical model, called the dual oscillator model, in which fast electrical oscillations are due to the feedback of

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Electrophysiology of Islet Cells,abolism-dependent alterations in ion channel activity..This coupling is best explored in beta cells. The effect of glucose is directly linked to mitochondrial metabolism as the ATP/ADP ratio determines the open probability of ATP-sensitive K. channels .K. channels). Nucleotide sensitivity and concen

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,High-Fat Programming of β-Cell Dysfunction,r insult during critical periods of life which includes fetal and subsequent early neonatal life. Programming alters progeny physiology and metabolism with immediate, transient, and durable effects. Maternal nutrition and metabolic state in gestation and lactation shapes progeny development and heal

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Titlebook: Islets of Langerhans; Md. Shahidul Islam Living reference work 20200th edition

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