唠叨
发表于 2025-3-23 11:22:11
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现晕光
发表于 2025-3-23 15:55:34
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察觉
发表于 2025-3-23 20:39:12
Cosimo Perrottainite proliferative potential in vitro (for review, see K. 1996). This process, termed growth transformation or immortalization, is supposed to be a prerequisite for the virus’ ability to establish life-long persistent infection in humans. Since similar signal pathways are activated and similar gene
沉默
发表于 2025-3-24 00:12:52
Cosimo Perrotta establish EBV-positive epithelial cell lines from EBV-infected gastric carcinoma tissues and to characterize the cell lines and EBV infection in the cells. EBV, a ubiquitous human herpesvirus with oncogenic potential, is predominantly associated with the infection of two target tissues in vivo: (1)
鉴赏家
发表于 2025-3-24 05:36:10
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Verify
发表于 2025-3-24 09:00:24
Cosimo Perrottancreasing number of human diseases. Generally considered the first human oncogenic virus because of a number of studies linking it with Burkitt‘s lymphoma and nasopharyngeal carcinoma (NPC), as well as its documented oncogenicity in nonhuman primates, EBVhas served as a model for identifying subsequ
使服水土
发表于 2025-3-24 13:49:24
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acrobat
发表于 2025-3-24 18:15:15
Cosimo Perrottatency (1). The BZLF1 (Z) protein is capable of binding to AP-1 sites as well as some sites unrelated to AP-1 (referred to as ZRE’s), and appears to function as a transcriptional transactivator through binding to these responsive promoter elements (2–5). However, it appears that the function of Z as
让步
发表于 2025-3-24 19:49:02
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MARS
发表于 2025-3-25 02:24:57
The second is “which other EB viral genes are activated as the result of ZEBRA expression?”.At least three variables have been identified which affect ZEBRA expression; these are genome rearrangements such as occur in defective virus, cell background, and the response to different inducing agents.