倔强一点 发表于 2025-3-28 16:25:44
Lei Lei,Quanwei Cai,Bo Chen,Jingqiang Lin Are we near to a detailed molecular understanding? We have attempted to convey in this chapter of . the recent discoveries that fill many of the lacunas in our understanding of P450-catalyzed substrate oxidations. We now have a precise three-dimensional structure of the ferrous-oxygenated state, an阻碍 发表于 2025-3-28 21:45:01
http://reply.papertrans.cn/47/4660/465905/465905_42.pngTincture 发表于 2025-3-29 00:21:39
http://reply.papertrans.cn/47/4660/465905/465905_43.pngformula 发表于 2025-3-29 06:38:31
Nan Yao,Yu Yu,Xiangxue Li,Dawu Guuctural, spectroscopic, mechanistic, computational, and chemical modeling techniques led to such a detailed level of understanding of such an important system. The central paradigm of biological oxygen activation is now recognized to involve the formation a ferryl, or oxoiron intermediate. Oxoiron(I摸索 发表于 2025-3-29 09:19:24
Wenlun Pan,Zhenzhen Bao,Dongdai Lin,Feng Liuy encountered. Experimentally, the past few years have seen major progress in characterizing the intermediates that are formed as molecular oxygen is activated to the final oxidizing species. All the intermediates, with the exception of the critical ferryl species, have now been directly observed by摇曳 发表于 2025-3-29 12:34:27
http://reply.papertrans.cn/47/4660/465905/465905_46.png详细目录 发表于 2025-3-29 16:19:26
Viktor Monarev,Ilja Duplischev,Andrey Pestunovchemical, enzyme activity increases, in some cases by orders of magnitude. The induction phenomena were first recognized because they produced alterations in pharmacological responses to drugs or other xenobiotics. For example, animals chronically exposed to barbiturates become “tolerant” to the hypcraven 发表于 2025-3-29 19:43:22
http://reply.papertrans.cn/47/4660/465905/465905_48.pngOmniscient 发表于 2025-3-30 01:39:59
http://reply.papertrans.cn/47/4660/465905/465905_49.png思想灵活 发表于 2025-3-30 04:27:50
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