GILD
发表于 2025-3-26 21:50:51
Spyros T. Halkidis,Alexander Chatzigeorgiou,George Stephanidesr predicting potential neurodegeneration, particularly following chronic brain hypoperfusion. This proposal is based on a series of experiments in rats subjected to mild chronic brain hypoperfusion and tested at determined time points for regional cytochrome oxidase activity, visuo-spatial memory, r
packet
发表于 2025-3-27 02:57:37
Yasunori Ishihara,Yumi Shimakawa,Toru Fujiwara that different individuals have different capacities to metabolize various drugs.. Such variation may result, in part, from an allelic distribution of P-450 isozymes;. or it may also result from individual variations in the level of a specific isozyme.. Also, deficiencies of different steroid hydro
结束
发表于 2025-3-27 09:12:16
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卵石
发表于 2025-3-27 11:26:41
Ilanit Moodahi,Ehud Gudes,Oz Lavee,Amnon Meiselstochrome P450 (CYP)-mediated metabolism. Therefore, hepatic clearance is undeniably one of the most critical pharmacokinetic parameters. In the early stages of drug discovery, the in vitro hepatic metabolic stability assay carries great importance as it provides a time- and cost-effective route for
有效
发表于 2025-3-27 15:59:42
Rakan El-Khalil,Angelos D. Keromytisue structures is small relative to the large number of P450s in Nature, it now is clear that the overall P450-fold is highly conserved and restricted to P450s and a small handful of other heme–thiolate enzymes. These crystal structures exhibit adaptations that underlie interactions with specific pro
septicemia
发表于 2025-3-27 21:03:01
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Morose
发表于 2025-3-27 23:13:11
Marcel Fernandez,Miguel Sorianoue structures is small relative to the large number of P450s in Nature, it now is clear that the overall P450-fold is highly conserved and restricted to P450s and a small handful of other heme–thiolate enzymes. These crystal structures exhibit adaptations that underlie interactions with specific pro
无法治愈
发表于 2025-3-28 05:02:25
Joaquin Garcia,Fabien Autrel,Joan Borrell,Sergio Castillo,Frederic Cuppens,Guillermo Navarroue structures is small relative to the large number of P450s in Nature, it now is clear that the overall P450-fold is highly conserved and restricted to P450s and a small handful of other heme–thiolate enzymes. These crystal structures exhibit adaptations that underlie interactions with specific pro
高深莫测
发表于 2025-3-28 09:42:42
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可卡
发表于 2025-3-28 14:07:54
Javier Lopez,Sihan Qing,Eiji OkamotoIncludes supplementary material: