Glutinous
发表于 2025-3-26 23:39:23
Dissolution Assay Development for , Correlations,e modified through changes in the dissolution test conditions. It is the goal of the pharmaceutical scientist to vary . conditions such that a dosage form or formulation series behaves in a manner similar to that found ..
经典
发表于 2025-3-27 02:50:41
Approaches to IVIVR Modelling and Statistical Analysis,ar model are proposed together with appropriate statistical methodology for fitting them. These models are shown to have some promise by using them to describe the . relationship for a number of batches of an extended release drug product.
引水渠
发表于 2025-3-27 06:39:19
Comparison of Methodologies for Evaluating Regional Intestinal Permeability,) of the intestinal lumen and intrinsic membrane permeability can further limit the bioavailability of drugs.. Recently, factors related to drug formulation such as particle size and shape, degradation and dissolution of the dosage form have been found to influence the absorption kinetics of drugs..
TAG
发表于 2025-3-27 09:30:42
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Altitude
发表于 2025-3-27 14:22:59
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ALIAS
发表于 2025-3-27 20:41:29
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esoteric
发表于 2025-3-27 22:03:13
Determination of Critical Manufacturing and Formulation Variables for a Hydrophilic Matrix Tablet FFormulation and manufacturing variables have been reported to influence the . release from hydrophilic matrix formulations. Studies on formulation and manufacturing variables have examined drug concentration. and particle size. polymer viscosity grade. and particle size. tablet compression force. and formulation additives..
DUCE
发表于 2025-3-28 06:10:10
Review of Methodologies for the Comparison of Dissolution Profile Data,Methods of comparing . dissolution profile data are of interest in the development of Extended Release dosage formulations. One is usually interested in determining if the dissolution profile for the Test formulation is significantly different from that of the Reference formulation. Some methods used to compare dissolution profiles include:
landmark
发表于 2025-3-28 07:45:44
Examples of , Relationships with a Diverse Range of Quality, to evaluate oral, modified-release formulations. Examples given are meant to portray applications to extended-release formulations, which may be defined as a dosage form allowing for a reduction in dosing frequency as compared to that drug presented as a conventional dosage form (1). “Controlled-re
突袭
发表于 2025-3-28 10:54:30
Dissolution Assay Development for , Correlations,concentration profile (e.g., AUC, Cmax, % Absorbed, etc.). The second data set is the . data. This is usually drug release data from a dissolution test and most often takes the form of percent dissolved as a function of time. A mathematical model describing the relationship between these data sets i