Prologue 发表于 2025-3-25 03:59:41
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T Cell-Mediated Immunity in the Immunosenescence Process,ise in the number and proportion of older persons worldwide, one of the challenges of a “long-life society” is to ensure that the years gained are not only healthy and disability-free years but also offering a good quality of life. In this perspective, recent research has concentrated on identifying减至最低 发表于 2025-3-25 15:29:28
Biological and Phenotypic Alterations of T Cells in Aging,oimmunity in elders. Ageing reduces the number and T cell potential of hematopoietic precursors, and involution of the thymus renders it less capable of supporting de novo T cell development. Consequently, ageing compromises the functions of lymphocytes, resulting in a T cell pool with restricted re前奏曲 发表于 2025-3-25 15:51:24
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Age-Related Alterations in Regulatory T Cells,geing affects different immune cell types, including hematopoietic stem cells, lymphoid progenitors in the bone marrow and thymus, thymic stromal cells, mature lymphocytes in secondary lymphoid organs, and elements of the innate immune system. Importantly, significant alterations are seen in the T lgruelling 发表于 2025-3-26 03:11:58
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The Role of MicroRNAs in Immunosenescence Process,. It has recently been recognized that proteins and genes involving in ageing process are precisely regulated by various MicroRNAs. MicroRNAs have been understood as pathway regulators in biological processes such as immune system component development and activation. MicroRNAs have crucial regulatojaundiced 发表于 2025-3-26 12:02:43
Immunogenetics of Aging,the humoral immune response decline with age. The individuals, genetically enriched for longevity, possess different immune signatures comparing to the general population. Human leukocyte antigen and cytokine gene polymorphisms are two examples with some associations with ageing. The genetic factorsFrequency-Range 发表于 2025-3-26 15:33:36
Optimizing Response to Vaccination in the Elderly,cination) a public health issue. However, normal vaccines that are effective in young and adult individuals are less immunogenic and less protective in the elderly, due to their impaired immune responsiveness. It is therefore necessary to design new vaccines especially suited to raise protective immorient 发表于 2025-3-26 17:36:42
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