Metamorphosis 发表于 2025-3-26 23:56:28
Evidence for frequent reactivation of the Oka varicella vaccine strain in healthy vaccinees,frequency of clinical sequelae and immunological boosting significantly exceeded the 13%/yr rate of exposure to wild type varicella. These findings indicate that the Oka strain of VZV persisted in vivo, and reactivated as serum antibody titers declined after vaccination. This mechanism may improve vaccine-associated long-term immunity.EVADE 发表于 2025-3-27 01:27:42
http://reply.papertrans.cn/47/4621/462079/462079_32.pngDefraud 发表于 2025-3-27 09:05:25
Investigation of varicella-zoster virus variation by heteroduplex mobility assay,. Of the 29 SNPs, eleven were non-synonymous and these were clustered in six genes. Isolates from a child and her mother to whom she had transmitted the virus, were identical at every locus tested. All other viruses could be distinguished by a combination of SNPs and length polymorphisms of the repeat regions R1, R2 and R5.Lime石灰 发表于 2025-3-27 13:13:36
Immune evasion mechanisms of varicella-zoster virus,s I and class II expression can be expected to interfere transiently with adaptive immune responses of the host, mediated by CD4 and CD8 T cells, ensuring that the virus has sufficient opportunity for transmission to susceptible contracts.Pelvic-Floor 发表于 2025-3-27 17:33:36
In vitro measurement of human T cell responses to varicella zoster virus antigen,ded to make comparisons possible. Cytokine-based methods for T lymphocyte responses may prove more sensitive, as may direct antigen-binding methods using tetramers of peptide and histocompatibility antigens — but experience with both is very limited.Legend 发表于 2025-3-27 20:35:21
Use of varicella vaccines to prevent herpes zoster in older individuals, mediated immunity exceeds 5 years. Although these trials have been hampered by uncertainty about the critical immune responses to evaluate, the stage is set for a double-blind, placebo-controlled trial of sufficient size to determine efficacy. Such a trial is now underway.品尝你的人 发表于 2025-3-28 01:49:04
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Conference proceedings 2001eld in 1 Osaka, Japan, March 8-10, 1999. Attendees included basic and clinical investi gators from Asia, Europe, and North America. The meeting was organized to explore progress made in basic virology and molecular understanding of varicella zoster (VZV), and to provide information on current knowl改正 发表于 2025-3-28 08:58:40
The current status of live attenuated varicella vaccine,ugh varicella is usually a mild illness, complications leading to morbidity and mortality are significant and the disease is worth preventing. The vaccine offers close to 100% protection from severe chickenpox and 90% protection from illness. Waning of immunity after vaccination, particularly in chiDOLT 发表于 2025-3-28 11:39:47
Evidence for frequent reactivation of the Oka varicella vaccine strain in healthy vaccinees,e. Anti-VZV titers declined over time in high-responder subjects, but rose in vaccinees with low titers. Among subjects with low anti-VZV titers, the frequency of clinical sequelae and immunological boosting significantly exceeded the 13%/yr rate of exposure to wild type varicella. These findings in