军械库 发表于 2025-3-27 00:50:55
http://reply.papertrans.cn/47/4621/462013/462013_31.png净礼 发表于 2025-3-27 03:05:43
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http://reply.papertrans.cn/47/4621/462013/462013_36.pngAUGUR 发表于 2025-3-28 01:54:40
G. Kopperschläger,J. Kirchberger to higher levels than their cognate linear mRNAs, but the vast majority are expressed at low levels. Hence, for most circRNAs, only a handful of sequencing reads, if any, that span the backsplicing junction are observed in standard RNA-seq libraries. It thus has become common to use the 3′–5′ exonu山顶可休息 发表于 2025-3-28 02:14:35
http://reply.papertrans.cn/47/4621/462013/462013_38.png原告 发表于 2025-3-28 09:33:23
Th. Schalkhammer,E. Mann-Buxbaum,I. Moser,G. Hawa,G. Urban,F. Pittnernique feature to interact with nucleic acids and ribonucleoproteins and are establishing themselves as an obligatory composition for the regulatory messages which are encoded by the genome. The back-splicing mechanism leads to the formation of circularized RNA, and because of this they become resistIrremediable 发表于 2025-3-28 10:43:41
D. Pum,M. Sára,U. B. Sleytrolyadenylated, single-stranded, covalently closed RNAs. CircRNAs are more stable than other RNAs due to lack of 5′ or 3′ end leading to resistance to exonuclease digestion. The length of circRNAs varies from 1 to 5 exons with retention of introns in mature circRNAs with ~25% frequency. They are prim