贵族 发表于 2025-3-23 12:23:19
Hubert Heinelt,Anne Lohmann therapyof T-cell prolymphocytic leukemia and T-cell large granular lymphocyte leukemia, two rare CLL-related entities, are addressed... .978-3-030-11392-6Series ISSN 2197-9766 Series E-ISSN 2197-9774MEEK 发表于 2025-3-23 15:27:20
the CLL and the aggressive lymphoma clones. Rituximab-containing polychemotherapy is the back-bone treatment in DLBCL-type RS. Young patients who respond to induction therapy should be offered stem cell transplant to prolong survival. ABVD-related regimen is the preferred regimen for the HL variant征服 发表于 2025-3-23 21:26:29
Hubert Heinelt,Anne Lohmannd potentially resulting in overexpression of BCL2, being an early feature of the disease in the majority of patients. However, genomic studies demonstrate a large array of additional molecular abnormalities with over 40 driver mutations potentially involved in the development of progressive disease.纠缠 发表于 2025-3-24 01:12:44
Hubert Heinelt,Anne Lohmannt when selecting time and type of treatment in CLL patients. We gained further knowledge on the role of B-cell receptor (BcR) signaling and accumulated several hints supporting its key role in CLL development and progression. This led, for the first time in CLL history, to a targeted treatment approGraduated 发表于 2025-3-24 04:38:45
Hubert Heinelt,Anne Lohmannd potentially resulting in overexpression of BCL2, being an early feature of the disease in the majority of patients. However, genomic studies demonstrate a large array of additional molecular abnormalities with over 40 driver mutations potentially involved in the development of progressive disease.分开如此和谐 发表于 2025-3-24 09:01:55
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are recognized, namely the diffuse large B-cell lymphoma (DLBCL) variant and the rare Hodgkin lymphoma (HL) variant. Histologic documentation is mandatory to diagnose RS. In the presence of clinical features suspicious of RS, diagnosis of transformation and choice of the site of biopsy may take adva我怕被刺穿 发表于 2025-3-25 01:30:10
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