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Rose Biggin reaction between N-acetoxy-N-2-acetyl-amino-fluorene (N-AcO-AAF) and DNA, several adducts are formed. Two of them have been identified as N-(deoxyguanosin-8-yl)-acetylaminofluorene and as 3(deoxyguanosin-N-2-yl)-acetylaminofluorene and they represent about 30% of the total adducts. The other adduct使迷醉 发表于 2025-3-22 08:08:26
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Rose Biggins to be done with caution..No simple rule can be derived for the relative rates of adduct removal from core- and linker-DNA in human cells. While the BPDE I guanine adducts were removed with similar efficiency from both DNA fractions the AAAF adducts disappeared much more rapidly from linker DNA ofanaphylaxis 发表于 2025-3-22 14:26:31
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978-3-319-87219-3The Editor(s) (if applicable) and The Author(s) 2017