burgeon 发表于 2025-3-21 16:20:07
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Prostacyclin and cerebral circulation interactions of neurohumoral origin and by a complex of interactions between the vessel wall and blood, first of all platelets. Determination of the vessel wall capacity to synthesize prostacyclin (PGI.) and assessment of its highly aggregatory and vasodilator effect on the one hand, and synthesis制定 发表于 2025-3-22 00:58:15
Effect of prostanoids on the coronary circulations concerning its role in various physiological and pathophysiological states. Due to its continuous formation in the vascular endothelium throughout the systemic and pulmonary circulatory systems the platelet anti-aggregatory effect of PGI. was considered to balance the pro-aggregatory effect of thrTexture 发表于 2025-3-22 06:29:09
Effects of aspirin and dazoxiben upon the peripheral circulation in mannous prostanoids. Aspirin, in doses of 300 mg or higher, inhibits both vascular and platelet cyclo-oxygenase (Hanley ., 1981; Preston ., 1981). This enzyme converts arachidonic acid, derived from the cell membrane, into the prostaglandin endoperoxides PGG. and PGH.. In blood vessels the major metabo–scent 发表于 2025-3-22 09:34:59
Controlled trials on the effects of prostacyclin in vascular diseasetrade names of Flolan (Wellcome) and Cycloprostin (Up-john). Vasodilatory and platelet-suppressant activities of prostacyclin . which had been described at the time of its discovery (Moncada ., 1976) were reproduced in healthy volunteers (Szczeklik ., 1978b; Gryglewski ., 1978). Those two propertiesSPURN 发表于 2025-3-22 14:20:33
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Formation and mechanism of action of leukotrienes: enzymatic hydration of leukotriene A4 by human bllogically active leukotrienes include LTC. [(5S,6R)-5-hydroxyl-6-(S-glutathionyl)-7,9-.11,14-.eicosatetraenoic acid] and its metabolites which are chemical constituents of slow reacting substances of anaphylaxis (Murphy ., 1979; Lewis ., 1980; Morris ., 1980; Orning ., 1980), and LTB. [(5S,12R)-5,12能得到 发表于 2025-3-22 22:52:01
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Actions of leukotrienes in the circulationtaining LTs, LTC., LTD., LTE. and LTF. are very active on some types of smooth muscle (see Piper, 1983) while LTB. is a very potent chemotactic agent for polymorphonuclear leucocytes (Ford-Hutchinson ., 1980). In addition to being among the most potent bronchoconstrictor agents known in human and gu