枪支 发表于 2025-3-25 05:19:57
The active site of phospholipase A2the active site. If one for example reacts the essential His 48 in phospholipase A. with an acylating reagent such as .-bromophenacyl-bromide all activity is lost. However the activity of phospholipase A. towards phospholipid micelles depends not only on the integrity of the active site itself, but羊齿 发表于 2025-3-25 08:05:46
Lipomodulin, a naturally occurring phospholipase A2 inhibitory proteinyunsaturated fatty acid, and is often found to be arachidonic acid, a precursor of prostaglandins and leukotrienes (Van Den Bosh, 1980). The latter compounds are well known to have diverse biological actions such as inflammation, pain, fever and so on (Kuehl & Egan, 1980). Lysophosphatidylcholine, t他去就结束 发表于 2025-3-25 13:36:13
Renocortin: a phospholipase A2 inhibitory protein induced by anti-inflammatory steroids: pharmacology, ribonucleic acid (RNA) and new protein synthesis (Russo-Marie ., 1979). As it had been previously demonstrated that steroids were inhibiting PG synthesis by inhibiting the release of arachidonic acid from their membrane phospholipid stores, probably by inhibiting the enzyme responsible for the phkidney 发表于 2025-3-25 16:01:26
Glucocorticoid-induced phospholipase inhibitory proteinsall the clinical signs and symptoms of acute and chronic inflammation, that is pain, redness, heat and swelling. Such profound effects of glucocorticoids are generally considered as ‘pharmacological actions’ since they are observed when amounts of steroids experimentally used in . or . studies are p游行 发表于 2025-3-25 23:59:53
The role of adrenaline in essential hypertension in manam, the plasma concentration must be increased several-fold — well above the range encountered during most daily activities — before any change in blood pressure is observed; and the change, when it occurs, is a fall in diastolic blood pressure together with increased systolic blood pressure (Clutte机械 发表于 2025-3-26 01:49:10
Glutathione and tissue toxicityde in a number of important cell functions. Thus, known physiological functions of glutathione now include maintenance of membrane integrity and cytoskeletal organization, involvement in protein and DNA synthesis, modification of protein conformation and enzyme activity, and promotion of neurotransmirreducible 发表于 2025-3-26 05:36:54
Symposium 13: Analysis of drug mechanisms by single ion channel recording — An Overviewe ion channels, each of which carries a current of the order of a picoampere. With a standard two-electrode voltage clamp the peak-to-peak baseline noise is at least 250 pA, so it was obviously impossible to resolve the currents through individual ion channels. The discovery by Neher & Sakmann of aantiquated 发表于 2025-3-26 10:50:57
http://reply.papertrans.cn/47/4606/460541/460541_28.png格子架 发表于 2025-3-26 13:43:55
http://reply.papertrans.cn/47/4606/460541/460541_29.pngFsh238 发表于 2025-3-26 17:23:28
http://reply.papertrans.cn/47/4606/460541/460541_30.png