oxidize
发表于 2025-3-25 03:56:22
clinical aspects of GI cancer, such as actionable targets and clinical trials using mutated ctDNA analysis, the significance of longitudinal observation of ctDNA for clonal evolution after targeted therapy, and the detection of minimal residual disease by ctDNA analysis. Finally, we summarize a few
Indelible
发表于 2025-3-25 07:52:37
to organs hosting a pre-metastatic niche, and finally the establishment of a metastatic lesion..Particular cancers usually metastasize to multiple but favored organ sites. The factors that determine organ-specific metastasis are: reciprocal recognition elements, such as integrins expressed by tumor
chronology
发表于 2025-3-25 13:08:33
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Femish
发表于 2025-3-25 18:11:34
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GRACE
发表于 2025-3-25 20:45:22
prevent the localization of these enzymes to the cell surface by blocking unique protease / integrin interactions. However, the critical keys to establishing these novel types of therapies involves an in-depth understanding of the basic molecular mechanisms that facilitate these protein-protein int
抗原
发表于 2025-3-26 00:10:06
d metastatic tumors. Tumors that over-expressed . RNA showed significantly higher rates of invasion and lymph node metastasis and tended to have higher rates of vascular involvement..Experimental inhibition of MTA1 protein expression using antisense phosphorothioate oligonucleotides resulted in grow
monopoly
发表于 2025-3-26 07:40:50
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Jacket
发表于 2025-3-26 10:41:52
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LARK
发表于 2025-3-26 13:46:30
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Fecal-Impaction
发表于 2025-3-26 17:32:17
on described for many peptide receptors at the plasma membrane, and is mainly ascribed to the activity of two families of proteases: matrix metalloproteinases (MMPs) and adamilysins (ADAMs). Ectodomain shedding of E-cadherin seems to be instrumental in the functional downregulation of the E-cadherin