圣歌
发表于 2025-3-25 06:40:32
Hypoxia and the Tumor Secretome,condary sites. Here we review current evidence for a hypoxia-induced tumor secretome and its impact on metastatic progression. These studies have identified potential biomarkers and therapeutic targets that could be integrated into strategies for preventing and treating metastatic disease.
泄露
发表于 2025-3-25 09:06:27
Therapeutic Strategies to Block the Hypoxic Response,FR/HER2 inhibitors also exist. Despite the existence of many therapeutics to combat the hypoxic response, there has been very little success in late phase clinical trials, potentially due to a lack of biomarkers that can be used to stratify patients who would benefit from a hypoxia-targeted therapy.
CRAB
发表于 2025-3-25 13:46:13
Hans J. Kleinsteuber,Meike Friesxygen (hypoxia) in malignant progression, and how hypoxia can be a significant factor in the development of drug resistance. We conclude by proposing potential therapeutic approaches that take advantage of a hypoxic microenvironment to chemosensitize therapy-resistant tumours.
伴随而来
发表于 2025-3-25 16:01:15
Hypoxia-Induced Resistance to Chemotherapy in Cancer,xygen (hypoxia) in malignant progression, and how hypoxia can be a significant factor in the development of drug resistance. We conclude by proposing potential therapeutic approaches that take advantage of a hypoxic microenvironment to chemosensitize therapy-resistant tumours.
CURT
发表于 2025-3-25 21:39:23
Das passende Schaubild finden ...,r of intratumoral hypoxia and controls hypoxia-mediated pathological processes in tumors, including angiogenesis, metabolic reprogramming, epigenetic reprogramming, immune evasion, pH homeostasis, cell migration/invasion, stem cell pluripotency, and therapy resistance. In this book chapter, we revie
退潮
发表于 2025-3-26 02:14:40
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团结
发表于 2025-3-26 04:30:50
Bibliothek des Radio Amateurs (geschlossen)he tumor microenvironment is strongly influenced by microenvironmental factors such as hypoxia. Clinically, hypoxia and the hypoxia inducible transcription factors HIF-1 and HIF-2 are associated with cancer stem cells, metastasis and drug resistance in multiple tumor types. Experimental models have
匍匐前进
发表于 2025-3-26 11:58:02
https://doi.org/10.1007/978-3-322-91055-4ic options will become available only if we enhance our understanding of mechanisms underlying metastatic spread. A large body of literature shows that the metastatic potential of tumor cells is strongly influenced by microenvironmental cues such as low oxygen (hypoxia). Clinically, hypoxia is a hal
凝乳
发表于 2025-3-26 16:30:57
Kurt Hesse,Rolf Fraling,Wolfgang Fralingmetastatic disease and mortality owing to its ability to stimulate the formation of blood (angiogenesis) and lymphatic vessels (lymphangiogenesis), thereby allowing cancer cells to escape the unfavorable tumor microenvironment and disseminate into secondary sites. This review outlines molecular mech
Obstruction
发表于 2025-3-26 18:35:52
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