易于出错
发表于 2025-3-26 22:13:41
Zebin Wu,Yang Xu,Jianjun Liurol. The methodology is applied to two previously studied designs. In the first design, patients with different biomarker levels are enrolled in a study and the treatment effect is assumed to be in ascending order of the biomarker level (a biomarker enrichment design). The goal of the interim analys
Culmination
发表于 2025-3-27 01:27:36
Tianzhu Liu,Yanfeng Guplasia, the ET as determined by TU could predict the presence or absence of hyperplasia. In response to the guidelines issued by regulatory authorities, ET from TU was utilized as a surrogate variable to impute the subject’s endometrial status (hyperplasia or no hyperplasia), in cases of an on-thera
Infantry
发表于 2025-3-27 07:00:21
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chisel
发表于 2025-3-27 09:56:09
Amanda Ziemann,Stefania Matteolid to facilitate drug development and provide some regulatory relief to a struggling industry. To achieve improvements in both safety and efficacy assessments as well as review timelines and consistency in reviews within the agency, the FDA will have to further consolidate medicinal product reviews i
Malcontent
发表于 2025-3-27 13:40:10
Shaoquan Zhang,Yuanchao Su,Xiang Xu,Jun Li,Chengzhi Deng,Antonio Plazaf the concerns and availability issues were resolved upon the emergence of recombinant DNA technology .. This technology has resulted in a proliferation of approved protein pharmaceuticals, which, by 1993, has amounted to $3 billion in sales in the United States. Although such issues as source avail
鄙视
发表于 2025-3-27 19:00:12
Jingxiang Yang,Yong-Qiang Zhao,Jonathan Cheung-Wai Chan, e.g., superoxide dismutase/catalase, or interact with the prostaglandin/leukotriene cascade .. Transfection of cells, specifically, cancer cells, with genes that generate presentation of nonself immune-responsive moieties at the cell surface, has led to the development of DNA vaccines, to date per
百灵鸟
发表于 2025-3-27 22:20:09
Ahmad W. Bitar,Jean-Philippe Ovarlez,Loong-Fah Cheong,Ali Chehabnufacturing processes. Qualified operators are the rare resource bottleneck to guarantee product quality. Therefore, continuous biomanufacturing as well as the consequent application of the quality by design approachare key-enablers towards biopharma 4.0.
玷污
发表于 2025-3-28 04:42:04
ity of upstream production. We then set out current challenges and trends in the upstream production and downstream processing phases of plant molecular farming. Finally, we discuss how these different elements can be combined into an integrated manufacturing facility based on plants and how this mi
PLUMP
发表于 2025-3-28 09:54:29
Wei Zhu,Zuoqiang Shi,Stanley Osherics covered include: Statistical Approaches to the Meta-analysis of Randomized Clinical Trials, Collaborative Targeted Maximum Likelihood Estimation to Assess Causal Effects in Observational Studies, Generalize978-981-13-4007-9978-981-10-7826-2Series ISSN 2199-0980 Series E-ISSN 2199-0999
Decongestant
发表于 2025-3-28 11:19:52
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