独行者 发表于 2025-3-28 16:02:26
http://reply.papertrans.cn/44/4305/430408/430408_41.pngHUSH 发表于 2025-3-28 20:52:34
W. Peschkas chapter describes the strategies as employed by the “From Gene to Lead” platform, including the major computer and experimental approaches and their interrelationship. The latter part of the chapter contains some examples of the steps required for implementing this platform.臆断 发表于 2025-3-29 00:18:29
http://reply.papertrans.cn/44/4305/430408/430408_43.pngTIA742 发表于 2025-3-29 03:48:10
M. Fischer,H. Eichertespect to the catalytic mechanisms. Proteins in distinct organisms are surprisingly homologous, reflecting considerable hysteresis in biological evolution; solutions of catalytic problems are only found once and then further copied. Appreciable similarities occur in the development and anatomy of di反应 发表于 2025-3-29 10:28:21
rsimony, likelihood, and Bayesian methods have been devised for estimating phylogenetic networks and associated parameters using estimated gene trees as data. Use of those inference methods has been augmented with statistical tests for specific hypotheses of hybridization, like the .-statistic. Most得罪 发表于 2025-3-29 12:14:43
G. Bauer and the use of supertree methods in divide-and-conquer strategies, and we identify directions where future research could lead to improved supertree methods. Finally, we present a new type of divide-and-conquer strategy that bypasses the need for supertree estimation, in which the division into subdelusion 发表于 2025-3-29 16:51:40
W. Schnurnberger,W. Seeger,H. Steebhm to compute the probability of the observed sequence of events. Both Viterbi and forward algorithms are dynamic programming algorithms that we were first exposed to in the chapter on sequence alignment. HMM is applied to reconstructing protein secondary structure as an illustrative example.DOLT 发表于 2025-3-29 22:18:36
, the term “molecular biologist” came handy. To get the crystallographer, biophysicist, biochemist,and geneticist within hi mself to collaborate with each other probably worked better than a team with a crystallographer, a biophysicist, a biochemist and a geneticist who maynot even be interested in证明无罪 发表于 2025-3-30 03:40:56
J. Nitsch,C. Voigt, the term “molecular biologist” came handy. To get the crystallographer, biophysicist, biochemist,and geneticist within hi mself to collaborate with each other probably worked better than a team with a crystallographer, a biophysicist, a biochemist and a geneticist who maynot even be interested in枕垫 发表于 2025-3-30 06:53:29
J. Nitsch,C. Voigt, the term “molecular biologist” came handy. To get the crystallographer, biophysicist, biochemist,and geneticist within hi mself to collaborate with each other probably worked better than a team with a crystallographer, a biophysicist, a biochemist and a geneticist who maynot even be interested in