gangrene
发表于 2025-3-28 17:33:27
Hyaluronan in Kidney Fibrosis, dynamically by the normal renal medulla to ensure whole-body fluid homeostasis. While levels of HA in the medulla fluctuate and can be very high, HA levels in the renal cortex remain static and are almost undetectable. Levels in the cortex are only upregulated in both acute and chronic renal diseas
非实体
发表于 2025-3-28 20:59:46
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Charade
发表于 2025-3-29 01:57:35
CD44: Does CD44v6 Adversely Impact the Prognosis of Cancer Patients?,e and metastasis. The ability of cancers to maintain tumorigenesis for a long term depends on a subpopulation of cancer cells, the self-renewing cancer-initiating cells (CICs) with cancer stem cell-like properties responsible for tumor initiation, progression, and drug resistance. The CICs can be id
labile
发表于 2025-3-29 05:01:31
The Pharmacokinetics and Pharmacodynamics of 4-Methylumbelliferone and its Glucuronide Metabolite ierone (4-MU), a small molecule inhibitor of HA synthases, is widely used to study HA’s interactions with the surrounding tissues and the immune cells. There is substantial experimental and therapeutic interest in using oral 4-MU to inhibit HA synthesis, but pharmacokinetic and pharmacodynamic data o
Frenetic
发表于 2025-3-29 08:58:01
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果仁
发表于 2025-3-29 12:38:14
Sulfated Hyaluronan: A Novel Player in Cancer Therapeutic and Bioengineering Approaches,ns, such as proliferation and migration, with its binding to its receptors CD44 and RHAMM triggering various signaling cascades. HA modifications regulate cellular responses in a different manner compared to unmodified HA fragments. The modified fragments are synthesized through a variety of strateg
Occupation
发表于 2025-3-29 17:23:55
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勉强
发表于 2025-3-29 23:12:42
Update on Hyaluronan in Development, make, break, interact with, and modify HA during some of these critical developmental milestones, with particular focus on HA in fertility, heart morphogenesis, intestinal morphogenesis, blood vascular development, and neonatal gut and lung development. We emphasize research advances that have been made in the last eight years.
键琴
发表于 2025-3-30 02:17:07
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lymphedema
发表于 2025-3-30 04:27:51
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