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1861-2253 Overview: Includes supplementary material: 978-3-642-09310-4978-3-540-73855-8Series ISSN 1861-2253 Series E-ISSN 1863-0685euphoria 发表于 2025-3-22 07:30:06
https://doi.org/10.1007/978-3-540-73855-8Cyclin E; breast cancer; estrogens; growth factor; hormone signaling; mitosis; nuclear receptors; prostrateright-atrium 发表于 2025-3-22 09:17:28
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DNA Replication Origins, Development, and Cancer, and its transmission to the offspring. In simple organisms, such as the bacteria ., a single DNA replication origin is used, fromwhich replication forksmigrate in opposite directions to allowthe duplication of the entire genome. In complex eukaryotes, such as multicellular organisms,multiple DNArepAUGUR 发表于 2025-3-23 00:59:41
Getting In and Out of Mitosis, genome, and how to prevent cell separation before chromosome segregation. Both these problems are solved by controlling when two specific proteins are destroyed: securin, an inhibitor of chromosome segregation, and cyclin B, which inhibits cell separation (cytokinesis). It has recently become clearabracadabra 发表于 2025-3-23 01:53:38
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A Novel Function for Cyclin E in Cell Cycle Progression,tant can reconstitute cyclin E’s function in cyclin E-null cells. Kinase-deficient cyclin E1 is loaded onto chromatin during G0 → S progression, it restores MCM incorporation and it facilitates S phase entry of cyclin E-null cells. We also observed that, in wild-type cells, cyclin E is loaded onto D