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Aromatase Overexpression: Effect of Tissue Estrogen on Phenotypic and Biochemical Changes in Aromatac activity are susceptible to carcinogens. The ARO overexpression-induced MG changes were inhibited with very low letrazole doses, an ARO inhibitor without any effect on normal physiology. The potential clinical importance of this intracrine growth support may provide future clinical and laboratory investigations.BURSA 发表于 2025-3-22 13:21:02
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Deregulation of Cyclin E and Genomic Instabilityrelative to the cell cycle, which can occur if the normal pathway of cyclin E turnover is inactivated. The resulting expression of cyclin E at inappropriate times of the cell cycle can then interfere with efficient progression through both S phase and M phase. Although not yet proven, we propose tha可以任性 发表于 2025-3-23 00:11:25
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Prostate Epithelial Carcinogenesis: Putative and Controversial Precursor Lesionsying genotype of PCA. This should set the stage for the development of new prognostic and therapeutic strategies. The understanding of genetic events which occur during the progression of PIN and other preneoplastic lesions to PCA would be useful for prevention, early detection, and treatment of thidebacle 发表于 2025-3-23 07:47:16
Estrogen Can Prevent Breast Cancer by Mimicking the Protective Effect of Pregnancy to MC. All are: susceptible to initiation and development of latent cancers; have a drastically reduced incidence of overt mammary cancers; have a decreased promotional environment with persistently reduced circulatory levels of GH and PRL, as well as a decreased expression of ERα and PRs in the ME