ARK 发表于 2025-3-25 05:23:34
Pressure Effects on the Intermolecular Interaction Potential of Condensed Protein Solutionsgregation, crystallization, and the phase behavior of proteins in general. Here, we report on a combined small-angle X-ray scattering and liquid-state theoretical approach to study dense lysozyme solutions as a function of temperature and pressure, but also in the presence of salts and osmolytes ofCOW 发表于 2025-3-25 09:30:39
High Pressure NMR Methods for Characterizing Functional Substates of Proteins In addition, these states can be characterized by their thermodynamic parameters, the free enthalpies at ambient pressure, the partial molar volumes, and the partial molar compressibility that can be obtained from the analysis of the high pressure NMR data. Two main types of states of proteins exis悬挂 发表于 2025-3-25 14:03:20
High-Pressure NMR Spectroscopy Reveals Functional Sub-states of Ubiquitin and Ubiquitin-Like Proteinstate N. and a locally disordered state I – between the basic folded state N. and totally unfolded U state. The high-energy states are conserved among ubiquitin-like post-translational modifiers, ubiquitin, NEDD8, and SUMO-2, showing the E1-E2-E3 cascade reaction. It is quite intriguing that structu谷类 发表于 2025-3-25 18:43:34
Functional Sub-states by High-pressure Macromolecular Crystallographyreover, within the context of high-pressure adaptation of deep-sea organisms, it allows to decipher the molecular determinants of piezophily. To provide an accurate description of structural changes produced by pressure in a macromolecular system, developments have been made to adapt macromolecular闹剧 发表于 2025-3-25 20:35:16
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Exploring the Protein Folding Pathway with High-Pressure NMR: Steady-State and Kinetics Studiesd in biophysical chemistry for over 50 years. Although a great deal of progress has been made in recent years towards this goal, a number of important questions remain. These include characterizing the structural, thermodynamic and dynamic properties of the barriers between conformational states on未成熟 发表于 2025-3-26 08:12:30
Basic Equations in Statics and Kinetics of Protein Polymerization and the Mechanism of the Formationive characterization of the protein fibrillation reaction with respect to volumetric parameters is necessary to elucidate mechanisms of amyloid fibrillation in molecular terms such as protein cavity and hydration. Here we discuss, firstly, basic equations in statics and kinetics of protein polymerizGenerosity 发表于 2025-3-26 09:39:20
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