Affirm
发表于 2025-3-26 21:37:10
Dominik Huber,Martin Schreiber,Martin Schulzulin diversity, which give rise to antigen binding heterodimers capable of responding to a wide spectrum of MHC-presented peptides. However, in this differentiation process only a small number of cells reach the mature state, as most are deleted by a process called negative selection (von . et al. 1
Cantankerous
发表于 2025-3-27 02:24:03
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陶瓷
发表于 2025-3-27 05:43:39
Jean-Baptiste Besnard,Ahmad Tarraf,Clément Barthélemy,Alberto Cascajo,Emmanuel Jeannot,Sameer Shende immune response and the onset of opportunistic infections and neoplasms. The mechanism responsible of CD4 T-cell depletion is mainly the induction of apoptosis, which can be activated by HIV through various pathways. In this chapter direct and indirect mechanisms of HIV-induced apoptosis in infecte
清醒
发表于 2025-3-27 12:25:54
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Pcos971
发表于 2025-3-27 14:52:01
resulting from a reciprocal t(9;22) translocation characterized by the formation of a shortened chromosome, named Philadelphia chromosome (Ph), in which the tyrosine kinase of c-ABL is constitutively activated. This chromosomal translocation generates . fusion genes which can be translated in three
贫穷地活
发表于 2025-3-27 19:52:47
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青石板
发表于 2025-3-27 21:58:18
Jonatan Baumgartner,Christophe Lillo,Sébastien Rumleyof metastasis can be conceptually broken down into a series of sequential steps: acquisition of an invasive phenotype, intravasation, travel through the circulatory system, arrest at a secondary site, and extravasation and colonization at that site. The metastatic cell must be able to escape cell de
健谈
发表于 2025-3-28 02:11:22
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ARIA
发表于 2025-3-28 09:20:47
Vincenzo De Maio,Ivona Brandicdamage response. The phosphorylation of H2AX on Ser 139, named γH2AX, is an early response to the generation of DNA DSBs and extends along megabase-long domains, both sites of the lesion, supporting amplification of signal transduction pathways. In parallel, 53BP1 accumulates on damaged chromatin to
hallow
发表于 2025-3-28 11:20:35
Fotis Nikolaidis,Antony Chazapis,Manolis Marazakis,Angelos Bilass macromolecules and organelles. During the last decade, progress made in our understanding of the molecular controls of autophagy has uncovered the importance of tumor suppressor molecules in the stimulation of autophagy. Downexpression of autophagy is an early event during tumorigenesis. However,