倾听 发表于 2025-3-26 23:16:28
http://reply.papertrans.cn/43/4263/426230/426230_31.png制定 发表于 2025-3-27 03:37:31
http://reply.papertrans.cn/43/4263/426230/426230_32.pngBureaucracy 发表于 2025-3-27 07:27:19
Rosa Poggianiapeutics focusing in particular on antisense oligonucleotide analogues carrying modifications in the backbone and sugar. Brief mention is made of siRNA development and other applications that have by and large utilized the same modifications. We also point out the pitfalls of the use of nucleic acid美食家 发表于 2025-3-27 11:23:46
Rosa Poggianid DNA backbones can cause immune activation which is concentration-and length-dependent and sequence-independent. However, the different backbones currently under development for antisense applications differ greatly in the degree to which they induce immune effects. As might be expected, neutral ba哀求 发表于 2025-3-27 15:39:16
http://reply.papertrans.cn/43/4263/426230/426230_35.pngenflame 发表于 2025-3-27 21:47:28
http://reply.papertrans.cn/43/4263/426230/426230_36.png革新 发表于 2025-3-27 22:36:09
reas (hereafter simply referred to as pancreatic cancer) occurs more frequently in African-Americans than in European-Americans. The disease progresses rapidly. Pancreatic cancer is usually refractory to treatment, with a median survival time of 12 mo. Overall, only 1% of patients live more than 5 yCoeval 发表于 2025-3-28 05:02:56
Rosa Poggianiides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery.Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous poten有偏见 发表于 2025-3-28 10:00:06
http://reply.papertrans.cn/43/4263/426230/426230_39.png异常 发表于 2025-3-28 11:23:03
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