旁观者
发表于 2025-3-27 00:00:36
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restrain
发表于 2025-3-27 01:21:17
HCV, Alcohol, and the Livern understanding of the various molecular cellular mechanisms by which HCV synergizes with alcohol to advance liver disease. Given the limited treatments available for HCV-infected patients who use alcohol, we also highlight new therapeutic targets and areas where more research would enhance our unde
nominal
发表于 2025-3-27 05:59:46
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荒唐
发表于 2025-3-27 10:06:16
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instate
发表于 2025-3-27 15:38:06
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sterilization
发表于 2025-3-27 19:58:21
HCV NS3/4A Protease Inhibitors and the Road to Effective Direct-Acting Antiviral Therapiesoof-of-concept in humans for a novel class of selective anti-HCV agents specifically designed to inhibit an essential viral enzyme. The inclusion of protease inhibitors with the standard of care therapy established the first major therapeutic advancement against HCV infection. In conjunction with ot
semiskilled
发表于 2025-3-28 02:00:52
Mechanism of Action of Direct-Acting Antivirals: New Insights into the HCV Life Cyclecomplex, viral RNA synthesis, and virion assembly. DAAs currently used in the clinic include inhibitors that target the NS3/4A protease, the NS5A protein, and the NS5B RNA-dependent RNA polymerase. This review will discuss the mode of action of each of the major classes of antiviral drugs and how th
钢笔尖
发表于 2025-3-28 04:21:11
Modeling HCV Dynamics in Clinical Practice to Personalize Antiviral Therapye residual number of infected cells at the end of therapy and its outcome, regardless to HCV genotype, IL28B polymorphism and characteristics of the liver disease. This modeling approach was successfully applied in a pilot study to tailor the duration of peg-interferon and ribavirin therapy, as well
秘方药
发表于 2025-3-28 08:22:35
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陈旧
发表于 2025-3-28 11:26:51
Global Control of Hepatitis C Virus Infection. Notably, risk factors and epidemiological parameters are very dynamic. To control HCV infection globally, we must establish a robust international network capable of monitoring the real time epidemiology of HCV and accounting for its increasing disease burden.