FLAIL 发表于 2025-3-30 11:23:22
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Pathobiology of Hepatitis B Virus-Induced Carcinogenesis, host genome occurs at early steps of clonal tumor expansion and induces both genomic instability and direct insertional mutagenesis of diverse cancer-related genes. Prolonged expression of the viral regulatory protein HBx and/or altered versions of the PreS/S envelope proteins deregulates cell tranVEIL 发表于 2025-3-30 20:20:30
Hepatitis B Virus: Persistence and Clearance,ions can be cleared by the adaptive immune response even after infection has spread to the entire hepatocyte population. Resolution of transient infections requires weeks and is associated with killing of a major fraction of infected hepatocytes by cytotoxic T lymphocytes (CTLs). Cytokines also playSolace 发表于 2025-3-30 23:47:00
Hepatitis Delta Virus: Virology and Replication,ion occurs only in humans infected with HBV, the HDV replication cycle includes that of the helper HBV. The HDV genome is a small circular single stranded RNA similar in structure to plant viroid RNA, which replicates in the cell nucleus through a rolling circle mechanism of RNA synthesis driven byGum-Disease 发表于 2025-3-31 04:00:50
Translational Medicine in Hepatitis B Virus: What Can We Learn from Clinical Samples?,ly controlled and where the impact of the effect of single genes, proteins, or cells can be consistently measured. Such reductionist approach cannot be applied in clinical samples, and for this reason experimental findings detected in clinical studies need to be defined in controlled models. On theQUAIL 发表于 2025-3-31 06:45:50
Global Epidemiology of Hepatitis B Virus Infection,ory of the epidemiology of hepatitis B represents a landmark in the general understanding of viral infections, their distributions and their outcomes. In 2010 and 2014 resolutions of the World Health Assembly, have acknowledged at the political level that viral hepatitis is a global public health prCholagogue 发表于 2025-3-31 12:49:12
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Natural History of HBV Infection in the Community,h complete recovery or death . As the pathological onset of a disease is not easy to define, the natural history of a disease may also be considered to start at the moment of exposure to causal agents . Knowledge of the natural history of disease is important for disease prevention and cont突袭 发表于 2025-4-1 01:28:23
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