驾驶 发表于 2025-3-26 23:02:15
Role of Synergism in the Pathogenesis of Hepatic Encephalopathy, and that other endogenous abnormalities augment the toxicity of these substances (Figure 1). Four of the substances that accumulate during hepatic failure have been shown unequivocally to cause coma in experimental animals. These are ammonia, mercaptans, fatty acids, and phenols. The role of ammon湿润 发表于 2025-3-27 01:46:41
γ-Aminobutyric Acid Receptors in Experimental Hepatic Encephalopathyblood, in cerebrospinal fluid or in brain with the aim of recognizing the primary factors leading to the central nervous system (CNS) dysfunction of coma. Because of the numerous metabolic abnormalities found in this pathology a congeries of theories has been generated, but none of these is so fullyCOW 发表于 2025-3-27 09:12:18
A Possible Role for Excitatory Neurotoxic Amino Acids in the Pathogenesis of Hepatic Encephalopathyral neurological and psychiatric disorders.. However, relatively little information is available on the role of glutamic acid (GLU), the prototype of acidic excitatory amino acids, in the pathogenesis of hepatic encephalopathy..争议的苹果 发表于 2025-3-27 10:57:20
http://reply.papertrans.cn/43/4257/425691/425691_34.png托人看管 发表于 2025-3-27 16:23:29
http://reply.papertrans.cn/43/4257/425691/425691_35.png善变 发表于 2025-3-27 19:11:39
http://reply.papertrans.cn/43/4257/425691/425691_36.png一小块 发表于 2025-3-27 22:16:24
Alterations of Plasma and Brain Tryptophan in Hepatic Encephalopathy: A Study in Humans and in Experchronic liver failure. In a group of 149 patients with liver cirrhosis, it was shown that plasma free tryptophan (the amino acid not bound to albumin) significantly rose when liver function was impaired. This increase was well correlated to the grade of hepatic encephalopathy. The ratio free tryptop有组织 发表于 2025-3-28 04:38:16
New Methods for the Determination of Serum and Breath Mercaptans and Its Application in Liver Cirrhos being one of the endogenous factors responsible for hepatic coma.. The reports in literature on breath. and serum or blood mercaptans. are highly conflicting. This is probably due to differences in assay and to technical difficulties to measure mercaptans in a reproducible way. The reports on seru不连贯 发表于 2025-3-28 08:42:03
http://reply.papertrans.cn/43/4257/425691/425691_39.png起来了 发表于 2025-3-28 12:56:53
Hepatic Encephalopathy is Associated with Decreased Numbers of Receptors for Excitatory Aminoacid Nes which are associated with liver failure and which could conceivably contribute to the mediation of this syndrome. Several observations have suggested that in liver failure impairment of cerebral neurotransmission may occur. In the “false neurotransmitter hypothesis” of the pathogenesis of HE propo