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Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease,he liver with the progressive induction of hepatocyte injury and secondary inflammation/fibrosis during the disease. A better understanding of the molecular and cellular pathway of lipotoxicity has both diagnostic and therapeutic implication for the treatment of NAFLD.摸索 发表于 2025-3-31 08:18:54
Hepatic Lipogenesis: Nutritional Control and Pathophysiological Relevance,ad to metabolic disorders such as non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease (CVD). In this article, nutrient composition and hormonal regulation of hepatic DNL, as well as the implication of hepatic DNL in contributing to metabolic diseases will be discussed in detail.Calibrate 发表于 2025-3-31 10:03:39
Metabolic Rhythm of Hepatic Lipogenesis: Regulation and Roles in Metabolism,ular clock and downstream nuclear receptors in the control of liver lipid metabolism. Potential mechanisms through which hepatic lipogenesis may affect peripheral metabolic homeostasis via lipid metabolites will also be discussed.